What is the recommended range for dialysate sodium concentration in hemodialysis?

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The recommended range for dialysate sodium concentration in hemodialysis is typically between 135 to 140 mEq/L. This concentration is considered ideal because it helps maintain a balance in sodium levels for patients undergoing dialysis, particularly those with chronic kidney disease.

Setting the sodium concentration within this range aims to prevent complications such as symptomatic hypotension or vascular access issues that can arise from fluctuations in sodium levels. It also facilitates the removal of excess sodium from the patient's blood while minimizing potential hypernatremia, which can be harmful.

Lower concentrations, such as those below 135 mEq/L, may lead to inadequate sodium removal, which could trigger complications for patients. Conversely, higher concentrations above 140 mEq/L may contribute to fluid overload and hypertension in dialysis patients, placing additional strain on their cardiovascular system. Thus, maintaining dialysate sodium within 135 to 140 mEq/L provides a therapeutic balance that supports patient safety and health during hemodialysis treatment.

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