What is the primary challenge associated with high-flux dialysis regarding infection?

The primary challenge associated with high-flux dialysis regarding infection lies in the presence of multiple pathogens. High-flux dialysis utilizes a dialyzer with larger pores, which allows for the removal of more toxins and larger molecules from the bloodstream. However, this increased permeability can also facilitate the entrance of pathogens, particularly bacteria, into the patient's bloodstream. The larger surface area and increased blood flow can enhance the risk of infections, especially if the hygiene practices are not strictly followed.

Additionally, high-flux dialysis is often used for patients who may be immunocompromised or have other underlying health issues that already increase their susceptibility to infections. This means that managing the risk and presence of multiple pathogens is crucial in maintaining patient safety during and after the dialysis process.